Cascade diagrams for depicting complex interventions in randomised trials

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Cascade diagrams for depicting complex interventions in randomised trials.

Manymedical interventions—particularly non-pharmacological ones—are complex, consisting of multiple interacting components targeted at different organisational levels. 2 Published descriptions of complex interventions often do not contain enough detail to enable their replication. Reports of behaviour change interventions should include descriptions of setting, mode, intensity, and duration, an...

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Randomised controlled trials of complex interventions

Although all randomised controlled trials (RCT) share much in common in terms of design, conduct, analysis and reporting, trials of complex interventions (loosely “interventions with several interacting components”) can have special issues which need appropriate consideration to deliver high quality and credible evidence to change or inform practice. For example, blinding the intervention may b...

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Process evaluation in randomised controlled trials of complex interventions.

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Process evaluations for cluster-randomised trials of complex interventions: a proposed framework for design and reporting

BACKGROUND Process evaluations are recommended to open the 'black box' of complex interventions evaluated in trials, but there is limited guidance to help researchers design process evaluations. Much current literature on process evaluations of complex interventions focuses on qualitative methods, with less attention paid to quantitative methods. This discrepancy led us to develop our own frame...

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Description of complex interventions: analysis of changes in reporting in randomised trials since 2002

BACKGROUND Inadequate description of non-pharmacological complex interventions in trial publications means that they cannot be replicated or assessed for generalisability. There are published guidelines on how to describe an intervention, such as those from the CONSORT Group. However, there have been few evaluations of whether intervention reporting is improving. METHODS We aimed to assess wh...

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ژورنال

عنوان ژورنال: BMJ

سال: 2013

ISSN: 1756-1833

DOI: 10.1136/bmj.f6681